Cargando…
Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling
Triple-negative breast cancer (TNBC) is a highly aggressive tumor subtype associated with a poor prognosis. The mechanism involved in TNBC progression remains largely unknown. To date, there are no effective therapeutic targets for this tumor subtype. In this study, by performing quantitative proteo...
Autores principales: | Jiang, Hong-Lin, Sun, He-Fen, Gao, Shui-Ping, Li, Liang-Dong, Hu, Xin, Wu, Jiong, Jin, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599274/ https://www.ncbi.nlm.nih.gov/pubmed/25970785 |
Ejemplares similares
-
Pirfenidone suppressed triple‐negative breast cancer metastasis by inhibiting the activity of the TGF‐β/SMAD pathway
por: Luo, Daiqin, et al.
Publicado: (2023) -
Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFβ/SMAD signaling pathway
por: Chen, Meng-Ting, et al.
Publicado: (2018) -
Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer
por: Singha, Prajjal K., et al.
Publicado: (2019) -
DGKZ promotes TGFβ signaling pathway and metastasis in triple-negative breast cancer by suppressing lipid raft-dependent endocytosis of TGFβR2
por: Zhao, Yuanyuan, et al.
Publicado: (2022) -
ICAM1 promotes bone metastasis via integrin‐mediated TGF‐β/EMT signaling in triple‐negative breast cancer
por: Chen, Mingcang, et al.
Publicado: (2022)