Cargando…

Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling

The role and underlying mechanism of Raf kinase inhibitory protein (RKIP) in nasopharyngeal carcinoma (NPC) metastasis remain unclear. Here, we showed that RKIP was downregulated in the NPC with high metastatic potentials, and its decrement correlated with NPC metastasis and poor patient survival, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Qiu-Yan, Yi, Hong-Mei, Yi, Hong, Xiao, Ta, Qu, Jia-Quan, Yuan, Li, Zhu, Jin-Feng, Li, Jiao-Yang, Wang, Yuan-Yuan, Li, Li-Na, Feng, Juan, Lu, Shan-Shan, Xiao, Zhi-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599279/ https://www.ncbi.nlm.nih.gov/pubmed/25915430

Ejemplares similares

Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity
por: Yuan, Li, et al.
Publicado: (2016)

MiR-23a sensitizes nasopharyngeal carcinoma to irradiation by targeting IL-8/Stat3 pathway
por: Jia-Quan, Qu, et al.
Publicado: (2015)

MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway
por: Zheng, Zhen, et al.
Publicado: (2017)

Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation
por: Zhu, Jin-Feng, et al.
Publicado: (2018)

miR-181a Upregulation Promotes Radioresistance of Nasopharyngeal Carcinoma by Targeting RKIP
por: Huang, Wei, et al.
Publicado: (2019)

Reduced RKIP expression levels are associated with frequent non-small cell lung cancer metastasis and STAT3 phosphorylation and activation
por: Wang, Ansheng, et al.
Publicado: (2017)

Integrated Analysis of Differential miRNA and mRNA Expression Profiles in Human Radioresistant and Radiosensitive Nasopharyngeal Carcinoma Cells
por: Li, Xin-Hui, et al.
Publicado: (2014)

RETRACTED ARTICLE: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p
por: Huang, Wei, et al.
Publicado: (2020)

Retraction Note: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/ NQO1 axis via downregulating miR-450b-5p
por: Huang, Wei, et al.
Publicado: (2023)

RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration
por: Datar, Ila, et al.
Publicado: (2015)

TROY interacts with RKIP to promote glioma development
por: Liu, Xiujie, et al.
Publicado: (2018)

Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance
por: Lin, Mei, et al.
Publicado: (2023)

HDAC7 promotes the oncogenicity of nasopharyngeal carcinoma cells by miR-4465-EphA2 signaling axis
por: Li, Qi-Guang, et al.
Publicado: (2020)

High-risk factors of parotid lymph node metastasis in nasopharyngeal carcinoma: a case-control study
por: Wang, Hong-zhi, et al.
Publicado: (2016)

Correction: RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration
por: Datar, Ila, et al.
Publicado: (2016)

Subdivision of Nasopharyngeal Carcinoma Patients with Bone-Only Metastasis at Diagnosis for Prediction of Survival and Treatment Guidance
por: Sun, Xue-Song, et al.
Publicado: (2019)

The biological complexity of RKIP signaling in human cancers
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2015)

RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer
por: Xie, Shi-Yang, et al.
Publicado: (2017)

Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway
por: Xiang, Yi-Ping, et al.
Publicado: (2020)

RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes
por: Bevilacqua, Elena, et al.
Publicado: (2012)

RKIP suppresses the influenza A virus-induced airway inflammatory response via the ERK/MAPK pathway
por: Ye, Jing-Jing, et al.
Publicado: (2022)

Development and validation of the immune signature to predict distant metastasis in patients with nasopharyngeal carcinoma
por: Liu, Sai-Lan, et al.
Publicado: (2020)

miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells
por: Li, Jipeng, et al.
Publicado: (2014)

Urinary RKIP/p-RKIP is a potential diagnostic and prognostic marker of clear cell renal cell carcinoma
por: Papale, Massimo, et al.
Publicado: (2017)

MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42
por: Wang, Yong-Xia, et al.
Publicado: (2016)

Molecular mechanism of hepatitis B virus (HBV) on suppression of raf kinase inhibitor protein (RKIP) expression
por: Cheng, Xiao-Ke, et al.
Publicado: (2016)

Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN)
por: Zhao, Yin, et al.
Publicado: (2020)

Post-treatment serum lactic dehydrogenase as a predictive indicator for distant metastasis and survival of patients with nasopharyngeal carcinoma
por: Wang, Jin, et al.
Publicado: (2016)

Longitudinal Trend of Health-Related Quality of Life During Concurrent Chemoradiotherapy and Survival in Patients With Stage II–IVb Nasopharyngeal Carcinoma
por: Li, Ji-Bin, et al.
Publicado: (2020)

Analysis of EGFR signaling pathway in nasopharyngeal carcinoma cells by quantitative phosphoproteomics
por: Ruan, Lin, et al.
Publicado: (2011)

NFAT1 Hypermethylation Promotes Epithelial-Mesenchymal Transition and Metastasis in Nasopharyngeal Carcinoma by Activating ITGA6 Transcription()()
por: Zhang, Jian, et al.
Publicado: (2019)

SHROOM2 inhibits tumor metastasis through RhoA–ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma
por: Yuan, Jing, et al.
Publicado: (2019)

Harnessing RKIP to Combat Heart Disease and Cancer
por: Lorenz, Kristina, et al.
Publicado: (2022)

Insights of RKIP-Derived Suppression of Prostate Cancer
por: Dong, Ying, et al.
Publicado: (2021)

The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment
por: Cessna, Hannah, et al.
Publicado: (2022)

RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact
por: Zaravinos, Apostolos, et al.
Publicado: (2018)

Raf Kinase Inhibitor Protein (RKIP) Blocks Signal Transducer and Activator of Transcription 3 (STAT3) Activation in Breast and Prostate Cancer
por: Yousuf, Saad, et al.
Publicado: (2014)

Analysis of risk characteristics for metachronous metastasis in different period of nasopharyngeal carcinoma
por: Fei, Zhaodong, et al.
Publicado: (2023)

RACK1 promotes tumorigenicity of colon cancer by inducing cell autophagy
por: Xiao, Ta, et al.
Publicado: (2018)

Correlation of five secretory proteins with the nasopharyngeal carcinoma metastasis and the clinical applications
por: Tao, Ya, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_luc9qht0cqau42kc1nf2r01dko