SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: whole-genome analysis in patients with hepatocellular carcinoma

Reliable biomarkers are required to predict the response to sorafenib. We investigated genomic variations associated with responsiveness to sorafenib for patients with unresectable hepatocellular carcinoma (HCC). Blood samples from 2 extreme, 2 strong and 3 poor responders to sorafenib were subjecte...

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Detalles Bibliográficos
Autores principales: Lee, Yeon-Su, Kim, Bo Hyun, Kim, Byung Chul, Shin, Aesun, Kim, Jin Sook, Hong, Seung-Hyun, Hwang, Jung-Ah, Lee, Jung Ahn, Nam, Seungyoon, Lee, Sung Hoon, Bhak, Jong, Park, Joong-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599281/
https://www.ncbi.nlm.nih.gov/pubmed/25965825

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