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ATRX represses alternative lengthening of telomeres
The unlimited proliferation of cancer cells requires a mechanism to prevent telomere shortening. Alternative Lengthening of Telomeres (ALT) is an homologous recombination-mediated mechanism of telomere elongation used in tumors, including osteosarcomas, soft tissue sarcoma subtypes, and glial brain...
Autores principales: | Napier, Christine E., Huschtscha, Lily I., Harvey, Adam, Bower, Kylie, Noble, Jane R., Hendrickson, Eric A., Reddel, Roger R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599288/ https://www.ncbi.nlm.nih.gov/pubmed/26001292 |
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