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Deguelin inhibits vasculogenic function of endothelial progenitor cells in tumor progression and metastasis via suppression of focal adhesion

Deguelin is a nature-derived chemopreventive drug. Endothelial progenitor cells (EPCs) are bone-marrow (BM)-derived key components to induce new blood vessels in early tumorigenesis and metastasis. Here we determined whether deguelin inhibits EPC function in vitro and in vivo at doses not affecting...

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Detalles Bibliográficos
Autores principales:	Nguyen, Minh Phuong, Lee, Dongjin, Lee, Se-Hyung, Lee, Hye-Eun, Lee, Ho-Young, Lee, You Mie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599291/ https://www.ncbi.nlm.nih.gov/pubmed/26078334

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