ERG deregulation induces IGF-1R expression in prostate cancer cells and affects sensitivity to anti-IGF-1R agents

Identifying patients who may benefit from targeted therapy is an urgent clinical issue in prostate cancer (PCa). We investigated the molecular relationship between TMPRSS2-ERG (T2E) fusion gene and insulin-like growth factor receptor (IGF-1R) to optimize the use of IGF-1R inhibitors. IGF-1R was anal...

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Detalles Bibliográficos
Autores principales: Mancarella, Caterina, Casanova-Salas, Irene, Calatrava, Ana, Ventura, Selena, Garofalo, Cecilia, Rubio-Briones, José, Magistroni, Vera, Manara, Maria Cristina, López-Guerrero, José Antonio, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599293/
https://www.ncbi.nlm.nih.gov/pubmed/25906745

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