Sequence specificity between interacting and non-interacting homologs identifies interface residues – a homodimer and monomer use case

BACKGROUND: Protein families participating in protein-protein interactions may contain sub-families that have different binding characteristics, ranging from right binding to showing no interaction at all. Composition differences at the sequence level in these sub-families are often decisive to thei...

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Detalles Bibliográficos
Autores principales: Hou, Qingzhen, Dutilh, Bas E., Huynen, Martijn A., Heringa, Jaap, Feenstra, K. Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599308/
https://www.ncbi.nlm.nih.gov/pubmed/26449222
http://dx.doi.org/10.1186/s12859-015-0758-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599308/
https://www.ncbi.nlm.nih.gov/pubmed/26449222
http://dx.doi.org/10.1186/s12859-015-0758-y

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