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Sequence specificity between interacting and non-interacting homologs identifies interface residues – a homodimer and monomer use case
BACKGROUND: Protein families participating in protein-protein interactions may contain sub-families that have different binding characteristics, ranging from right binding to showing no interaction at all. Composition differences at the sequence level in these sub-families are often decisive to thei...
Autores principales: | Hou, Qingzhen, Dutilh, Bas E., Huynen, Martijn A., Heringa, Jaap, Feenstra, K. Anton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599308/ https://www.ncbi.nlm.nih.gov/pubmed/26449222 http://dx.doi.org/10.1186/s12859-015-0758-y |
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