Use of Whole Exome Sequencing for the Identification of I(to)-Based Arrhythmia Mechanism and Therapy

BACKGROUND: Identified genetic variants are insufficient to explain all cases of inherited arrhythmia. We tested whether the integration of whole exome sequencing with well-established clinical, translational, and basic science platforms could provide rapid and novel insight into human arrhythmia pa...

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Detalles Bibliográficos
Autores principales: Sturm, Amy C, Kline, Crystal F, Glynn, Patric, Johnson, Benjamin L, Curran, Jerry, Kilic, Ahmet, Higgins, Robert S D, Binkley, Philip F, Janssen, Paul M L, Weiss, Raul, Raman, Subha V, Fowler, Steven J, Priori, Silvia G, Hund, Thomas J, Carnes, Cynthia A, Mohler, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599408/
https://www.ncbi.nlm.nih.gov/pubmed/26015324
http://dx.doi.org/10.1161/JAHA.114.001762

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