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Hydrogen Sulfide Levels and Nuclear Factor-Erythroid 2-Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)

BACKGROUND: Cystathionine γ-lyase, cystathionine β-synthase, and 3-mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide (H(2)S). Functions of H(2)S are mediated by several targets including ion channels and signaling proteins. Nuclear factor-erythroid 2-related fac...

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Detalles Bibliográficos
Autores principales:	Islam, Kazi N, Polhemus, David J, Donnarumma, Erminia, Brewster, Luke P, Lefer, David J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599428/ https://www.ncbi.nlm.nih.gov/pubmed/25977470 http://dx.doi.org/10.1161/JAHA.115.001986

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