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Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells

Tongue squamous cell carcinoma (TSCC) is the most common malignancy in oral and maxillofacial tumors with highly metastatic characteristics. Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone; PLB), a natural naphthoquinone derived from the roots of Plumbaginaceae plants, exhibits various bioactiviti...

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Detalles Bibliográficos
Autores principales:	Pan, Shu-Ting, Qin, Yiru, Zhou, Zhi-Wei, He, Zhi-Xu, Zhang, Xueji, Yang, Tianxin, Yang, Yin-Xue, Wang, Dong, Zhou, Shu-Feng, Qiu, Jia-Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599573/ https://www.ncbi.nlm.nih.gov/pubmed/26491260 http://dx.doi.org/10.2147/DDDT.S89621

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