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Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing
A 69-year-old man was diagnosed with IgG λ-type multiple myeloma (MM), Stage II in October 2010. He was treated with one cycle of high-dose dexamethasone. After three cycles of bortezomib, the patient exhibited slow elevations in the free light-chain levels and developed a significant new increase o...
Autores principales: | Ikeda, Hiroshi, Ishiguro, Kazuya, Igarashi, Tetsuyuki, Aoki, Yuka, Hayashi, Toshiaki, Ishida, Tadao, Sasaki, Yasushi, Tokino, Takashi, Shinomura, Yasuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599646/ https://www.ncbi.nlm.nih.gov/pubmed/26491355 http://dx.doi.org/10.2147/OTT.S86515 |
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