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Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS
Recent advances in techniques for manipulating genomes have allowed the generation of transgenic animals other than mice. These new models enable cross-mammalian comparison of neurological disease from core cellular pathophysiology to circuit and behavioural endophenotypes. Moreover they will enable...
Autores principales: | Till, Sally M., Asiminas, Antonis, Jackson, Adam D., Katsanevaki, Danai, Barnes, Stephanie A., Osterweil, Emily K., Bear, Mark F., Chattarji, Sumantra, Wood, Emma R., Wyllie, David J.A., Kind, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599667/ https://www.ncbi.nlm.nih.gov/pubmed/26243794 http://dx.doi.org/10.1093/hmg/ddv299 |
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