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Unexpected Trypsin Cleavage at Ubiquitinated Lysines

[Image: see text] Unexpected tryptic cleavage has been characterized at modified K48 residues in polyubiquitins. In particular, the tryptic products of all seven of the lysine-linked dimers of ubiquitin and of three trimers—linear Ub–(48)Ub–(48)Ub, linear Ub–(63)Ub–(63)Ub, and the branched trimer [U...

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Detalles Bibliográficos
Autores principales:	Burke, Meghan C., Wang, Yan, Lee, Amanda E., Dixon, Emma Kimm, Castaneda, Carlos A., Fushman, David, Fenselau, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599693/ https://www.ncbi.nlm.nih.gov/pubmed/26182167 http://dx.doi.org/10.1021/acs.analchem.5b01960

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