A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store

Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subcellular compartment requires tools that are optimiz...

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Detalles Bibliográficos
Autores principales: Henderson, Mark J., Baldwin, Heather A., Werley, Christopher A., Boccardo, Stefano, Whitaker, Leslie R., Yan, Xiaokang, Holt, Graham T., Schreiter, Eric R., Looger, Loren L., Cohen, Adam E., Kim, Douglas S., Harvey, Brandon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599735/
https://www.ncbi.nlm.nih.gov/pubmed/26451944
http://dx.doi.org/10.1371/journal.pone.0139273

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