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Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults
Loci identified in genome-wide association studies (GWAS) of cardio-metabolic traits account for a small proportion of the traits' heritability. To date, most association studies have not considered parent-of-origin effects (POEs). Here we report investigation of POEs on adiposity and glycemic...
Autores principales: | Hochner, Hagit, Allard, Catherine, Granot-Hershkovitz, Einat, Chen, Jinbo, Sitlani, Colleen M., Sazdovska, Sandra, Lumley, Thomas, McKnight, Barbara, Rice, Kenneth, Enquobahrie, Daniel A., Meigs, James B., Kwok, Pui, Hivert, Marie-France, Borecki, Ingrid B., Gomez, Felicia, Wang, Ting, van Duijn, Cornelia, Amin, Najaf, Rotter, Jerome I., Stamatoyannopoulos, John, Meiner, Vardiella, Manor, Orly, Dupuis, Josée, Friedlander, Yechiel, Siscovick, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599806/ https://www.ncbi.nlm.nih.gov/pubmed/26451733 http://dx.doi.org/10.1371/journal.pgen.1005573 |
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