Organosilane and Polyethylene Glycol Functionalized Magnetic Mesoporous Silica Nanoparticles as Carriers for CpG Immunotherapy In Vitro and In Vivo

Cytosine–guanine (CpG) containing oligodeoxynucleotides (ODN) have significant clinical potential as immunotherapeutics. However, limitations exist due to their transient biological stability in vivo, lack of specificity for target cells, and poor cellular uptake. To address these issues, we prepare...

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Detalles Bibliográficos
Autores principales: Zheng, Hengrui, Wen, Songsong, Zhang, Yang, Sun, Zhenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599948/
https://www.ncbi.nlm.nih.gov/pubmed/26451735
http://dx.doi.org/10.1371/journal.pone.0140265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599948/
https://www.ncbi.nlm.nih.gov/pubmed/26451735
http://dx.doi.org/10.1371/journal.pone.0140265

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