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Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex

Human immunodeficiency virus type 1 (HIV-1) Nef enhances virus replication and contributes to immune evasion in vivo, but the underlying molecular mechanisms remain incompletely defined. Nef interferes with host cell actin dynamics to restrict T lymphocyte responses to chemokine stimulation and T ce...

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Detalles Bibliográficos
Autores principales:	Imle, Andrea, Abraham, Libin, Tsopoulidis, Nikolaos, Hoflack, Bernard, Saksela, Kalle, Fackler, Oliver T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600113/ https://www.ncbi.nlm.nih.gov/pubmed/26350970 http://dx.doi.org/10.1128/mBio.01309-15

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