Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide. Previously, we and others established models for DENV pathogenesis in mice that completely lack subunits of the receptors (Ifnar and Ifng...

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Detalles Bibliográficos
Autores principales: Pinto, Amelia K., Brien, James D., Lam, Chia-Ying Kao, Johnson, Syd, Chiang, Cindy, Hiscott, John, Sarathy, Vanessa V., Barrett, Alan D., Shresta, Sujan, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600115/
https://www.ncbi.nlm.nih.gov/pubmed/26374123
http://dx.doi.org/10.1128/mBio.01316-15

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