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Blastomyces Virulence Adhesin-1 Protein Binding to Glycosaminoglycans Is Enhanced by Protein Disulfide Isomerase

Blastomyces adhesin-1 (BAD-1) protein mediates the virulence of the yeast Blastomyces dermatitidis, in part by binding host lung tissue, the extracellular matrix, and cellular receptors via glycosaminoglycans (GAGs), such as heparan sulfate. The tandem repeats that make up over 90% of BAD-1 appear i...

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Detalles Bibliográficos
Autores principales:	Beaussart, Audrey, Brandhorst, Tristan, Dufrêne, Yves F., Klein, Bruce S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600121/ https://www.ncbi.nlm.nih.gov/pubmed/26396244 http://dx.doi.org/10.1128/mBio.01403-15

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