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Aluminum Nanoholes for Optical Biosensing

Sub-wavelength diameter holes in thin metal layers can exhibit remarkable optical features that make them highly suitable for (bio)sensing applications. Either as efficient light scattering centers for surface plasmon excitation or metal-clad optical waveguides, they are able to form strongly locali...

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Autores principales: Barrios, Carlos Angulo, Canalejas-Tejero, Víctor, Herranz, Sonia, Urraca, Javier, Moreno-Bondi, María Cruz, Avella-Oliver, Miquel, Maquieira, Ángel, Puchades, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600165/
https://www.ncbi.nlm.nih.gov/pubmed/26184330
http://dx.doi.org/10.3390/bios5030417
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author Barrios, Carlos Angulo
Canalejas-Tejero, Víctor
Herranz, Sonia
Urraca, Javier
Moreno-Bondi, María Cruz
Avella-Oliver, Miquel
Maquieira, Ángel
Puchades, Rosa
author_facet Barrios, Carlos Angulo
Canalejas-Tejero, Víctor
Herranz, Sonia
Urraca, Javier
Moreno-Bondi, María Cruz
Avella-Oliver, Miquel
Maquieira, Ángel
Puchades, Rosa
author_sort Barrios, Carlos Angulo
collection PubMed
description Sub-wavelength diameter holes in thin metal layers can exhibit remarkable optical features that make them highly suitable for (bio)sensing applications. Either as efficient light scattering centers for surface plasmon excitation or metal-clad optical waveguides, they are able to form strongly localized optical fields that can effectively interact with biomolecules and/or nanoparticles on the nanoscale. As the metal of choice, aluminum exhibits good optical and electrical properties, is easy to manufacture and process and, unlike gold and silver, its low cost makes it very promising for commercial applications. However, aluminum has been scarcely used for biosensing purposes due to corrosion and pitting issues. In this short review, we show our recent achievements on aluminum nanohole platforms for (bio)sensing. These include a method to circumvent aluminum degradation—which has been successfully applied to the demonstration of aluminum nanohole array (NHA) immunosensors based on both, glass and polycarbonate compact discs supports—the use of aluminum nanoholes operating as optical waveguides for synthesizing submicron-sized molecularly imprinted polymers by local photopolymerization, and a technique for fabricating transferable aluminum NHAs onto flexible pressure-sensitive adhesive tapes, which could facilitate the development of a wearable technology based on aluminum NHAs.
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spelling pubmed-46001652015-10-15 Aluminum Nanoholes for Optical Biosensing Barrios, Carlos Angulo Canalejas-Tejero, Víctor Herranz, Sonia Urraca, Javier Moreno-Bondi, María Cruz Avella-Oliver, Miquel Maquieira, Ángel Puchades, Rosa Biosensors (Basel) Article Sub-wavelength diameter holes in thin metal layers can exhibit remarkable optical features that make them highly suitable for (bio)sensing applications. Either as efficient light scattering centers for surface plasmon excitation or metal-clad optical waveguides, they are able to form strongly localized optical fields that can effectively interact with biomolecules and/or nanoparticles on the nanoscale. As the metal of choice, aluminum exhibits good optical and electrical properties, is easy to manufacture and process and, unlike gold and silver, its low cost makes it very promising for commercial applications. However, aluminum has been scarcely used for biosensing purposes due to corrosion and pitting issues. In this short review, we show our recent achievements on aluminum nanohole platforms for (bio)sensing. These include a method to circumvent aluminum degradation—which has been successfully applied to the demonstration of aluminum nanohole array (NHA) immunosensors based on both, glass and polycarbonate compact discs supports—the use of aluminum nanoholes operating as optical waveguides for synthesizing submicron-sized molecularly imprinted polymers by local photopolymerization, and a technique for fabricating transferable aluminum NHAs onto flexible pressure-sensitive adhesive tapes, which could facilitate the development of a wearable technology based on aluminum NHAs. MDPI 2015-07-09 /pmc/articles/PMC4600165/ /pubmed/26184330 http://dx.doi.org/10.3390/bios5030417 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barrios, Carlos Angulo
Canalejas-Tejero, Víctor
Herranz, Sonia
Urraca, Javier
Moreno-Bondi, María Cruz
Avella-Oliver, Miquel
Maquieira, Ángel
Puchades, Rosa
Aluminum Nanoholes for Optical Biosensing
title Aluminum Nanoholes for Optical Biosensing
title_full Aluminum Nanoholes for Optical Biosensing
title_fullStr Aluminum Nanoholes for Optical Biosensing
title_full_unstemmed Aluminum Nanoholes for Optical Biosensing
title_short Aluminum Nanoholes for Optical Biosensing
title_sort aluminum nanoholes for optical biosensing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600165/
https://www.ncbi.nlm.nih.gov/pubmed/26184330
http://dx.doi.org/10.3390/bios5030417
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