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BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses

Control of histone acetylation is a part of the epigenetic mechanism that regulates gene expression and chromatin architecture. The members of the bromodomain and extra terminal domain (BET) protein family are a group of epigenetic readers that recognize histone acetylation, whereas histone deacetyl...

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Detalles Bibliográficos
Autores principales:	Kokkola, Tarja, Suuronen, Tiina, Pesonen, Maija, Filippakopoulos, Panagis, Salminen, Antero, Jarho, Elina M, Lahtela-Kakkonen, Maija
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600234/ https://www.ncbi.nlm.nih.gov/pubmed/26212199 http://dx.doi.org/10.1002/cbic.201500272

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