Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour

BACKGROUND: Patients with breast cancer have an increased risk of developing subsequent breast cancers. It is important to distinguish whether these tumours are de novo or recurrences of the primary tumour in order to guide the appropriate therapy. Our aim was to investigate the use of DNA methylati...

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Detalles Bibliográficos
Autores principales: Huang, Katie T., Mikeska, Thomas, Li, Jason, Takano, Elena A., Millar, Ewan K A, Graham, Peter H., Boyle, Samantha E., Campbell, Ian G., Speed, Terence P., Dobrovic, Alexander, Fox, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600279/
https://www.ncbi.nlm.nih.gov/pubmed/26452468
http://dx.doi.org/10.1186/s12885-015-1676-0

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