Cargando…
Shank2 Regulates Renal Albumin Endocytosis
Albuminuria is a strong and independent predictor of kidney disease progression but the mechanisms of albumin handling by the kidney remain to be fully defined. Previous studies have shown that podocytes endocytose albumin. Here we demonstrate that Shank2, a large scaffolding protein originally iden...
Autores principales: | Dobrinskikh, Evgenia, Lewis, Linda, Doctor, R Brian, Okamura, Kayo, Lee, Min Goo, Altmann, Christopher, Faubel, Sarah, Kopp, Jeffrey B, Blaine, Judith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600376/ https://www.ncbi.nlm.nih.gov/pubmed/26333830 http://dx.doi.org/10.14814/phy2.12510 |
Ejemplares similares
-
Endocytosis of Albumin by Podocytes Elicits an Inflammatory Response and Induces Apoptotic Cell Death
por: Okamura, Kayo, et al.
Publicado: (2013) -
Podocytes Degrade Endocytosed Albumin Primarily in Lysosomes
por: Carson, John M., et al.
Publicado: (2014) -
Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo
por: Dylewski, James, et al.
Publicado: (2019) -
Intratracheal IL-6 Protects against Lung Inflammation in Direct, but Not Indirect, Causes of Acute Lung Injury in Mice
por: Bhargava, Rhea, et al.
Publicado: (2013) -
Prolonged acute kidney injury exacerbates lung inflammation at 7 days post‐acute kidney injury
por: Andres‐Hernando, Ana, et al.
Publicado: (2014)