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17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats

Prevalence of metabolic syndrome and progression of nephropathy depend on sex. We examined a protective effect of estradiol against nephropathy in metabolic syndrome through the modulation of the arachidonic acid metabolism by activating the 5-lipoxygenase and cytochrome p450 4A pathways. 28 female...

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Detalles Bibliográficos
Autores principales:	Zúñiga-Muñoz, A. M., Guarner Lans, V., Soria-Castro, E., Diaz-Diaz, E., Torrico-Lavayen, R., Tena-Betancourt, E., Pérez-Torres, I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600504/ https://www.ncbi.nlm.nih.gov/pubmed/26491436 http://dx.doi.org/10.1155/2015/149408

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