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Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line
Overexpression of efflux transporters, in human cells, is a mechanism of resistance to drug and also to chemotherapy. We found that multidrug resistance protein-4 (MRP4) overexpression has a role in reducing aspirin action in patients after bypass surgery and, very recently, we found that aspirin en...
Autores principales: | Massimi, Isabella, Ciuffetta, Ambra, Temperilli, Flavia, Ferrandino, Francesca, Zicari, Alessandra, Pulcinelli, Fabio M., Felli, Maria Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600549/ https://www.ncbi.nlm.nih.gov/pubmed/26491233 http://dx.doi.org/10.1155/2015/607957 |
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