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Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line

Overexpression of efflux transporters, in human cells, is a mechanism of resistance to drug and also to chemotherapy. We found that multidrug resistance protein-4 (MRP4) overexpression has a role in reducing aspirin action in patients after bypass surgery and, very recently, we found that aspirin en...

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Detalles Bibliográficos
Autores principales: Massimi, Isabella, Ciuffetta, Ambra, Temperilli, Flavia, Ferrandino, Francesca, Zicari, Alessandra, Pulcinelli, Fabio M., Felli, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600549/
https://www.ncbi.nlm.nih.gov/pubmed/26491233
http://dx.doi.org/10.1155/2015/607957

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