Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

Idiopathic pulmonary fibrosis (IPF) is an age-related fatal disease with unknown etiology and no effective treatment. In this study, we show that primary cultures of fibroblasts derived from lung biopsies of IPF patients exhibited (i) accelerated replicative cellular senescence (CS); (ii) high resis...

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Detalles Bibliográficos
Autores principales: Yanai, Hagai, Shteinberg, Albert, Porat, Ziv, Budovsky, Arie, Braiman, Alex, Zeische, Rolf, Fraifeld, Vadim E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600624/
https://www.ncbi.nlm.nih.gov/pubmed/26399448

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