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The loss of LRPPRC function induces the mitochondrial unfolded protein response

The inactivation of the LRPPRC gene, which has previously been associated with the neurodegenerative French Canadian Leigh Syndrome, results in a decrease in the production of mitochondria-encoded subunits of complex IV, thereby causing a reduction in complex IV activity. Previously we have shown th...

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Detalles Bibliográficos
Autores principales: Köhler, Fabian, Müller-Rischart, Anne Kathrin, Conradt, Barbara, Rolland, Stéphane Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600627/
https://www.ncbi.nlm.nih.gov/pubmed/26412102