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Attenuation of p38α MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells
Functional competence and self-renewal of mammalian skeletal muscle myofibers and progenitor cells declines with age. Progression of the muscle aging phenotype involves the decline of juvenile protective factors i.e., proteins whose beneficial functions translate directly to the quality of life, and...
Autores principales: | Papaconstantinou, John, Wang, Chen Z., Zhang, Min, Yang, San, Deford, James, Bulavin, Dmitry V., Ansari, Naseem H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600628/ https://www.ncbi.nlm.nih.gov/pubmed/26423835 |
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