Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells

The aetiology of human fibrolamellar hepatocellular carcinomas (hFL-HCCs), cancers occurring increasingly in children to young adults, is poorly understood. We present a transplantable tumour line, maintained in immune-compromised mice, and validate it as a bona fide model of hFL-HCCs by multiple me...

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Detalles Bibliográficos
Autores principales: Oikawa, Tsunekazu, Wauthier, Eliane, Dinh, Timothy A., Selitsky, Sara R., Reyna-Neyra, Andrea, Carpino, Guido, Levine, Ronald, Cardinale, Vincenzo, Klimstra, David, Gaudio, Eugenio, Alvaro, Domenico, Carrasco, Nancy, Sethupathy, Praveen, Reid, Lola M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600730/
https://www.ncbi.nlm.nih.gov/pubmed/26437858
http://dx.doi.org/10.1038/ncomms9070

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