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Acidic phospholipids govern the enhanced activation of IgG-B cell receptor

B cells that express the isotype-switched IgG-B cell receptor (IgG-BCR) are one of the driving forces for antibody memory. To allow for a rapid memory IgG antibody response, IgG-BCR evolved into a highly effective signalling machine. Here, we report that the positively charged cytoplasmic domain of...

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Detalles Bibliográficos
Autores principales: Chen, Xiangjun, Pan, Weiling, Sui, Yinqiang, Li, Hua, Shi, Xiaoshan, Guo, Xingdong, Qi, Hai, Xu, Chenqi, Liu, Wanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600742/
https://www.ncbi.nlm.nih.gov/pubmed/26440273
http://dx.doi.org/10.1038/ncomms9552

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