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Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
Myelin regeneration can occur spontaneously in demyelinating diseases such as multiple sclerosis (MS). However, the underlying mechanisms and causes of its frequent failure remain incompletely understood. Here we show, using an in-vivo remyelination model, that demyelinated axons are electrically ac...
Autores principales: | Gautier, Hélène O. B., Evans, Kimberley A., Volbracht, Katrin, James, Rachel, Sitnikov, Sergey, Lundgaard, Iben, James, Fiona, Lao-Peregrin, Cristina, Reynolds, Richard, Franklin, Robin J. M., Káradóttir, Ragnhildur T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600759/ https://www.ncbi.nlm.nih.gov/pubmed/26439639 http://dx.doi.org/10.1038/ncomms9518 |
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