Cargando…

Genome-wide association study identifies multiple susceptibility loci for glioma

Previous genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of glioma. To identify new glioma susceptibility loci, we conducted a meta-analysis of four GWAS (totalling 4,147 cases and 7,435 controls), with imputation using 1000 Genomes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kinnersley, Ben, Labussière, Marianne, Holroyd, Amy, Di Stefano, Anna-Luisa, Broderick, Peter, Vijayakrishnan, Jayaram, Mokhtari, Karima, Delattre, Jean-Yves, Gousias, Konstantinos, Schramm, Johannes, Schoemaker, Minouk J., Fleming, Sarah J., Herms, Stefan, Heilmann, Stefanie, Schreiber, Stefan, Wichmann, Heinz-Erich, Nöthen, Markus M., Swerdlow, Anthony, Lathrop, Mark, Simon, Matthias, Bondy, Melissa, Sanson, Marc, Houlston, Richard S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600760/ https://www.ncbi.nlm.nih.gov/pubmed/26424050 http://dx.doi.org/10.1038/ncomms9559

Ejemplares similares

Search for new loci and low-frequency variants influencing glioma risk by exome-array analysis
por: Kinnersley, Ben, et al.
Publicado: (2016)

Quantifying the heritability of glioma using genome-wide complex trait analysis
por: Kinnersley, Ben, et al.
Publicado: (2015)

Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222
por: Enciso-Mora, V, et al.
Publicado: (2013)

Leveraging Ethnic Group Incidence Variation to Investigate Genetic Susceptibility to Glioma: A Novel Candidate SNP Approach
por: Jacobs, Daniel I., et al.
Publicado: (2012)

Tumor and Endothelial Cell Hybrids Participate in Glioblastoma Vasculature
por: El Hallani, Soufiane, et al.
Publicado: (2014)

Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition
por: Broderick, Peter, et al.
Publicado: (2006)

Maternal breast cancer risk in relation to birthweight and gestation of her offspring
por: Swerdlow, Anthony J., et al.
Publicado: (2018)

Author Correction: Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2
por: Studd, James B., et al.
Publicado: (2018)

Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2
por: Studd, James B., et al.
Publicado: (2017)

Common variation at 10p12.31 near MLLT10 influences meningioma risk
por: Dobbins, Sara E, et al.
Publicado: (2011)

IDH Mutations: Genotype-Phenotype Correlation and Prognostic Impact
por: Wang, Xiao-Wei, et al.
Publicado: (2014)

Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin’s Lymphoma
por: Frampton, Matthew, et al.
Publicado: (2013)

Smoking and risk of breast cancer in the Generations Study cohort
por: Jones, Michael E., et al.
Publicado: (2017)

Breast cancer risk in relation to history of preeclampsia and hyperemesis gravidarum: Prospective analysis in the Generations Study
por: Wright, Lauren B., et al.
Publicado: (2018)

Family history and risk of breast cancer: an analysis accounting for family structure
por: Brewer, Hannah R., et al.
Publicado: (2017)

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
por: Vijayakrishnan, Jayaram, et al.
Publicado: (2018)

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
por: Vijayakrishnan, Jayaram, et al.
Publicado: (2019)

TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations
por: Labussière, M, et al.
Publicado: (2014)

Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes
por: Dobbins, Sara E., et al.
Publicado: (2016)

Mortality and Cancer Incidence in Carriers of Balanced Robertsonian Translocations: A National Cohort Study
por: Schoemaker, Minouk J, et al.
Publicado: (2019)

Mortality and cancer incidence in carriers of constitutional t(11;22)(q23;q11) translocations: A prospective study
por: Schoemaker, Minouk J, et al.
Publicado: (2019)

Risk of breast cancer in men in relation to weight change: A national case‐control study in England and Wales
por: Swerdlow, Anthony J., et al.
Publicado: (2022)

Genome-wide association analysis identifies a meningioma risk locus at 11p15.5
por: Claus, Elizabeth B, et al.
Publicado: (2018)

Length of FMR1 repeat alleles within the normal range does not substantially affect the risk of early menopause
por: Ruth, Katherine S., et al.
Publicado: (2016)

Childhood body size and pubertal timing in relation to adult mammographic density phenotype
por: Schoemaker, Minouk J., et al.
Publicado: (2017)

Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study
por: Johns, Louise E, et al.
Publicado: (2018)

Reply to ‘Comment on ‘Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study”
por: Johns, Louise E, et al.
Publicado: (2018)

Response to ‘Comment on ‘Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study”
por: Johns, Louise E, et al.
Publicado: (2018)

Response to ‘Comment on ‘Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study”
por: Johns, Louise E., et al.
Publicado: (2018)

Diffuse gliomas classified by 1p/19q co-deletion, TERT promoter and IDH mutation status are associated with specific genetic risk loci
por: Labreche, Karim, et al.
Publicado: (2018)

Mendelian randomisation study of the relationship between vitamin D and risk of glioma
por: Takahashi, Hannah, et al.
Publicado: (2018)

Publisher Correction: Mendelian randomisation study of the relationship between vitamin D and risk of glioma
por: Takahashi, Hannah, et al.
Publicado: (2019)

DNA methylation of the long intergenic noncoding RNA 299 gene in triple-negative breast cancer: results from a prospective study
por: Manoochehri, Mehdi, et al.
Publicado: (2020)

Genetic predisposition to B-cell acute lymphoblastic leukemia at 14q11.2 is mediated by a CEBPE promoter polymorphism
por: Studd, James B., et al.
Publicado: (2018)

Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study
por: Bodicoat, Danielle H, et al.
Publicado: (2014)

Psychological stress, adverse life events and breast cancer incidence: a cohort investigation in 106,000 women in the United Kingdom
por: Schoemaker, Minouk J., et al.
Publicado: (2016)

Reply to Comment on: “Night shift work and risk of breast cancer in women: the Generations Study cohort”
por: Jones, Michael E., et al.
Publicado: (2019)

Night shift work and risk of breast cancer in women: the Generations Study cohort
por: Jones, Michael E., et al.
Publicado: (2019)

Correction to: Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study
por: Bodicoat, Danielle H., et al.
Publicado: (2020)

Algorithmic considerations when analysing capture Hi-C data
por: Disney-Hogg, Linden, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ohl72fvcvd4n799c2cf7bnnsbp