Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus

Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as...

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Autores principales: Iruretagoyena, Mirentxu, Hirigoyen, Daniela, Naves, Rodrigo, Burgos, Paula Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600954/
https://www.ncbi.nlm.nih.gov/pubmed/26528285
http://dx.doi.org/10.3389/fimmu.2015.00513
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author Iruretagoyena, Mirentxu
Hirigoyen, Daniela
Naves, Rodrigo
Burgos, Paula Isabel
author_facet Iruretagoyena, Mirentxu
Hirigoyen, Daniela
Naves, Rodrigo
Burgos, Paula Isabel
author_sort Iruretagoyena, Mirentxu
collection PubMed
description Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity, and possible effects of supplementation in disease treatment.
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spelling pubmed-46009542015-11-02 Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus Iruretagoyena, Mirentxu Hirigoyen, Daniela Naves, Rodrigo Burgos, Paula Isabel Front Immunol Immunology Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity, and possible effects of supplementation in disease treatment. Frontiers Media S.A. 2015-10-12 /pmc/articles/PMC4600954/ /pubmed/26528285 http://dx.doi.org/10.3389/fimmu.2015.00513 Text en Copyright © 2015 Iruretagoyena, Hirigoyen, Naves and Burgos. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Iruretagoyena, Mirentxu
Hirigoyen, Daniela
Naves, Rodrigo
Burgos, Paula Isabel
Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus
title Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus
title_full Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus
title_fullStr Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus
title_full_unstemmed Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus
title_short Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus
title_sort immune response modulation by vitamin d: role in systemic lupus erythematosus
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600954/
https://www.ncbi.nlm.nih.gov/pubmed/26528285
http://dx.doi.org/10.3389/fimmu.2015.00513
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