Ring finger protein 166 potentiates RNA virus-induced interferon-β production via enhancing the ubiquitination of TRAF3 and TRAF6

Host cells orchestrate the production of IFN-β upon detecting invading viral pathogens. Here, we report that Ring finger protein 166 (RNF166) potentiates RNA virus-triggered IFN-β production. Overexpression of RNF166 rather than its homologous proteins RNF114, RNF125, and RNF138, enhanced Sendai vir...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hai-Wei, Yang, Yong-Kang, Xu, Hao, Yang, Wei-Wei, Zhai, Zhong-He, Chen, Dan-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600972/
https://www.ncbi.nlm.nih.gov/pubmed/26456228
http://dx.doi.org/10.1038/srep14770

Ejemplares similares

Ejemplares similares