Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets

Ghost cell odontogenic carcinoma (GCOC) is an exceedingly rare malignant tumor on the spectrum of already uncommon odontogenic or dentinogenic tumors. We describe here the case of metastatic GCOC in a patient with a history of recurrent dentinogenic ghost cell tumor of the mandible, now presenting w...

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Autores principales: Rappaport, Maximilien J., Showell, Darion L., Edenfield, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600987/
https://www.ncbi.nlm.nih.gov/pubmed/26500725
http://dx.doi.org/10.4081/rt.2015.5813
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author Rappaport, Maximilien J.
Showell, Darion L.
Edenfield, William J.
author_facet Rappaport, Maximilien J.
Showell, Darion L.
Edenfield, William J.
author_sort Rappaport, Maximilien J.
collection PubMed
description Ghost cell odontogenic carcinoma (GCOC) is an exceedingly rare malignant tumor on the spectrum of already uncommon odontogenic or dentinogenic tumors. We describe here the case of metastatic GCOC in a patient with a history of recurrent dentinogenic ghost cell tumor of the mandible, now presenting with bilateral pleural effusions. We will discuss typical histopathologic and histochemical features of GCOC, along with results of genomic testing and their role in directing therapy.
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spelling pubmed-46009872015-10-23 Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets Rappaport, Maximilien J. Showell, Darion L. Edenfield, William J. Rare Tumors Case Report Ghost cell odontogenic carcinoma (GCOC) is an exceedingly rare malignant tumor on the spectrum of already uncommon odontogenic or dentinogenic tumors. We describe here the case of metastatic GCOC in a patient with a history of recurrent dentinogenic ghost cell tumor of the mandible, now presenting with bilateral pleural effusions. We will discuss typical histopathologic and histochemical features of GCOC, along with results of genomic testing and their role in directing therapy. PAGEPress Publications, Pavia, Italy 2015-09-07 /pmc/articles/PMC4600987/ /pubmed/26500725 http://dx.doi.org/10.4081/rt.2015.5813 Text en ©Copyright M.J. Rappaportet al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rappaport, Maximilien J.
Showell, Darion L.
Edenfield, William J.
Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
title Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
title_full Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
title_fullStr Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
title_full_unstemmed Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
title_short Metastatic Ghost Cell Odontogenic Carcinoma: Description of a Case and Search for Actionable Targets
title_sort metastatic ghost cell odontogenic carcinoma: description of a case and search for actionable targets
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600987/
https://www.ncbi.nlm.nih.gov/pubmed/26500725
http://dx.doi.org/10.4081/rt.2015.5813
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