Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia

Neurodegenerative diseases have been linked to inflammation, but whether altered immunomodulation plays a causative role in neurodegeneration is not clear. We show that lack of cytokine interferon-β (IFN-β) signaling causes spontaneous neurodegeneration in the absence of neurodegenerative disease-ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Ejlerskov, Patrick, Hultberg, Jeanette Göransdotter, Wang, JunYang, Carlsson, Robert, Ambjørn, Malene, Kuss, Martin, Liu, Yawei, Porcu, Giovanna, Kolkova, Kateryna, Friis Rundsten, Carsten, Ruscher, Karsten, Pakkenberg, Bente, Goldmann, Tobias, Loreth, Desiree, Prinz, Marco, Rubinsztein, David C., Issazadeh-Navikas, Shohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601085/
https://www.ncbi.nlm.nih.gov/pubmed/26451483
http://dx.doi.org/10.1016/j.cell.2015.08.069

Ejemplares similares

Ejemplares similares