Cargando…

Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding

Amyotrophic lateral sclerosis (ALS), a fatal adult-onset degenerative neuromuscular disorder with a poorly defined etiology, progresses in an orderly spatiotemporal manner from one or more foci within the nervous system, reminiscent of prion disease pathology. We have previously shown that misfolded...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grad, Leslie I, Pokrishevsky, Edward, Silverman, Judith M, Cashman, Neil R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Extra View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601269/ https://www.ncbi.nlm.nih.gov/pubmed/25551548 http://dx.doi.org/10.4161/19336896.2014.983398

Ejemplares similares

TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion
por: Pokrishevsky, Edward, et al.
Publicado: (2016)

Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection
por: Crown, Anthony, et al.
Publicado: (2020)

Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity
por: Sporn, Zachary A, et al.
Publicado: (2015)

RML prions act through Mahogunin and Attractin-independent pathways
por: Gunn, Teresa M, et al.
Publicado: (2013)

Potential approaches for heterologous prion protein treatment of prion diseases
por: Seelig, Davis M., et al.
Publicado: (2015)

Disease-associated protein seeding suggests a dissociation between misfolded protein accumulation and neurodegeneration in prion disease
por: Alibhai, James, et al.
Publicado: (2017)

An insight into the complex prion-prion interaction network in the budding yeast Saccharomyces cerevisiae
por: Du, Zhiqiang, et al.
Publicado: (2014)

Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain
por: Mabbott, Neil A.
Publicado: (2012)

Life cycle of cytosolic prions
por: Hofmann, Julia, et al.
Publicado: (2013)

Porcine prion protein amyloid
por: Hammarström, Per, et al.
Publicado: (2015)

Protein misfolding in Dictyostelium: Using a freak of nature to gain insight into a universal problem
por: Malinovska, Liliana, et al.
Publicado: (2015)

Neuronal zinc regulation and the prion protein
por: Watt, Nicole T., et al.
Publicado: (2013)

Getting to the core of prion superstructural variability
por: Torrent, Joan, et al.
Publicado: (2015)

On the reactive states of astrocytes in prion diseases
por: Baskakov, Ilia V.
Publicado: (2021)

Structural conservation of prion strain specificities in recombinant prion protein fibrils in real-time quaking-induced conversion
por: Sano, Kazunori, et al.
Publicado: (2015)

Protective role of MyD88-independent innate immune responses against prion infection
por: Ishibashi, Daisuke, et al.
Publicado: (2012)

Controlling the prion propensity of glutamine/asparagine-rich proteins
por: Paul, Kacy R, et al.
Publicado: (2015)

Aβ seeds and prions: How close the fit?
por: Rasmussen, Jay, et al.
Publicado: (2017)

Transgenic mice recapitulate the phenotypic heterogeneity of genetic prion diseases without developing prion infectivity: Role of intracellular PrP retention in neurotoxicity
por: Chiesa, Roberto, et al.
Publicado: (2016)

The prion protein family: Looking outside the central nervous system
por: Passet, Bruno, et al.
Publicado: (2013)

Saccharomyces cerevisiae: A sexy yeast with a prion problem
por: Kelly, Amy C., et al.
Publicado: (2013)

New insights into structural determinants of prion protein folding and stability
por: Benetti, Federico, et al.
Publicado: (2015)

The prion-ZIP connection: From cousins to partners in iron uptake
por: Singh, Neena, et al.
Publicado: (2015)

Could yeast prion domains originate from polyQ/N tracts?
por: Alexandrov, Alexander I., et al.
Publicado: (2013)

Functions of the cellular prion protein, the end of Moore's law, and Ockham's razor theory
por: del Río, José A., et al.
Publicado: (2016)

Prion-specific Hsp40 function: The role of the auxilin homolog Swa2
por: Oliver, Emily E., et al.
Publicado: (2017)

The story of stolen chaperones: How overexpression of Q/N proteins cures yeast prions
por: Derkatch, Irina L, et al.
Publicado: (2013)

Sup35 methionine oxidation is a trigger for de novo [PSI(+)] prion formation
por: Grant, Chris M
Publicado: (2015)

Profilin 1 mutants form aggregates that induce accumulation of prion-like TDP-43
por: Tanaka, Yoshinori, et al.
Publicado: (2016)

Wild-type Cu/Zn-superoxide dismutase is misfolded in cerebrospinal fluid of sporadic amyotrophic lateral sclerosis
por: Tokuda, Eiichi, et al.
Publicado: (2019)

Prions on the run: How extracellular vesicles serve as delivery vehicles for self-templating protein aggregates
por: Liu, Shu, et al.
Publicado: (2017)

Prion protein and susceptibility to kainate-induced seizures: Genetic pitfalls in the use of PrP knockout mice
por: Striebel, James F, et al.
Publicado: (2013)

Transmissibility of Gerstmann–Sträussler–Scheinker syndrome in rodent models: New insights into the molecular underpinnings of prion infectivity
por: Nonno, Romolo, et al.
Publicado: (2016)

How structure shapes (dys)function: A perspective to understanding brain region-specific degeneration in prion disease
por: Šišková, Zuzana
Publicado: (2013)

The Cu, Zn Superoxide Dismutase: Not Only a Dismutase Enzyme
por: Mondola, Paolo, et al.
Publicado: (2016)

A seeded propagation of Cu, Zn-superoxide dismutase aggregates in amyotrophic lateral sclerosis
por: Ogawa, Mariko, et al.
Publicado: (2014)

Identifying critical sites of PrP(c)-PrP(Sc) interaction in prion-infected cells by dominant-negative inhibition
por: Taguchi, Yuzuru, et al.
Publicado: (2013)

Is the prevalent human prion protein 129M/V mutation a living fossil from a Paleolithic panzootic superprion pandemic?
por: Nyström, Sofie, et al.
Publicado: (2014)

Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)
por: Gupta, Govind, et al.
Publicado: (2022)

Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis
por: Pokrishevsky, Edward, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_p018b5kvhahnl3hmvehrnjfhs7