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Role of Oxidative and Nitrosative Stress in Pathophysiology of Toxic Epidermal Necrolysis and Stevens Johnson Syndrome—A Pilot Study

BACKGROUND: Oxidative and nitrosative stress caused by drug metabolism may be a trigger for keratinocyte apoptosis in the epidermis seen in toxic epidermal necrolysis (TEN) and Stevens Johnson syndrome (SJS). AIMS: To estimate oxidative damage in the serum and to examine the role of nitric oxide in...

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Detalles Bibliográficos
Autores principales: Peter, Dincy, Amirtharaj, G Jayakumar, Mathew, Teena, Pulimood, Susanne, Ramachandran, Anup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601406/
https://www.ncbi.nlm.nih.gov/pubmed/26538686
http://dx.doi.org/10.4103/0019-5154.159617