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Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases

BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional s...

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Autores principales: Sehgal, Virendra N, Srivastava, Govind, Aggarwal, Ashok K, Saxena, Deepti, Chatterjee, Kingshuk, Khurana, Ananta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601437/
https://www.ncbi.nlm.nih.gov/pubmed/26538716
http://dx.doi.org/10.4103/0019-5154.164412
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author Sehgal, Virendra N
Srivastava, Govind
Aggarwal, Ashok K
Saxena, Deepti
Chatterjee, Kingshuk
Khurana, Ananta
author_facet Sehgal, Virendra N
Srivastava, Govind
Aggarwal, Ashok K
Saxena, Deepti
Chatterjee, Kingshuk
Khurana, Ananta
author_sort Sehgal, Virendra N
collection PubMed
description BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional supplements also play essential roles. Its diagnosis has been perpetuated by three or more major/minor criteria. OBJECTIVES: An endeavor to study its demographic and clinical pattern in contemporary prospective. MATERIALS AND METHODS: 100 fresh patients of atopic dermatitis, diagnosed on the basis of an established three or more major and minor criteria, salient presentations of which were recorded in a preset proforma, which also recorded age, duration, age of onset, and sex. Serum immunoglobulin E (IgE) levels were determined by conventional technique. The data thus obtained was analysed to study its clinical pattern and to correlate its severity to IgE levels. RESULTS: Its overall (new and old) prevalence was 0.98%, while that of new patients was 0.24%. 83 (83%) were in the age group of 2-12 years, of which 54 (83.1%) were males and 29 (82.9%) were female, of which 70 (70%) had urban, while 30 (30%) had rural background. Its duration varied from 8 to 192 weeks, with a mean of 76 weeks, and a standard deviation of 21.42 weeks [76 ± 21.42]. CONCLUSION: Atopic dermatitis is a discrete, overt, age and IgE-related entity frequently displaying varying demographic and clinical connotation.
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spelling pubmed-46014372015-11-04 Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases Sehgal, Virendra N Srivastava, Govind Aggarwal, Ashok K Saxena, Deepti Chatterjee, Kingshuk Khurana, Ananta Indian J Dermatol E-IJD Original Article BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional supplements also play essential roles. Its diagnosis has been perpetuated by three or more major/minor criteria. OBJECTIVES: An endeavor to study its demographic and clinical pattern in contemporary prospective. MATERIALS AND METHODS: 100 fresh patients of atopic dermatitis, diagnosed on the basis of an established three or more major and minor criteria, salient presentations of which were recorded in a preset proforma, which also recorded age, duration, age of onset, and sex. Serum immunoglobulin E (IgE) levels were determined by conventional technique. The data thus obtained was analysed to study its clinical pattern and to correlate its severity to IgE levels. RESULTS: Its overall (new and old) prevalence was 0.98%, while that of new patients was 0.24%. 83 (83%) were in the age group of 2-12 years, of which 54 (83.1%) were males and 29 (82.9%) were female, of which 70 (70%) had urban, while 30 (30%) had rural background. Its duration varied from 8 to 192 weeks, with a mean of 76 weeks, and a standard deviation of 21.42 weeks [76 ± 21.42]. CONCLUSION: Atopic dermatitis is a discrete, overt, age and IgE-related entity frequently displaying varying demographic and clinical connotation. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4601437/ /pubmed/26538716 http://dx.doi.org/10.4103/0019-5154.164412 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle E-IJD Original Article
Sehgal, Virendra N
Srivastava, Govind
Aggarwal, Ashok K
Saxena, Deepti
Chatterjee, Kingshuk
Khurana, Ananta
Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
title Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
title_full Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
title_fullStr Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
title_full_unstemmed Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
title_short Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
title_sort atopic dermatitis: a cross-sectional (descriptive) study of 100 cases
topic E-IJD Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601437/
https://www.ncbi.nlm.nih.gov/pubmed/26538716
http://dx.doi.org/10.4103/0019-5154.164412
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