Cargando…
Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases
BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional s...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601437/ https://www.ncbi.nlm.nih.gov/pubmed/26538716 http://dx.doi.org/10.4103/0019-5154.164412 |
_version_ | 1782394551033397248 |
---|---|
author | Sehgal, Virendra N Srivastava, Govind Aggarwal, Ashok K Saxena, Deepti Chatterjee, Kingshuk Khurana, Ananta |
author_facet | Sehgal, Virendra N Srivastava, Govind Aggarwal, Ashok K Saxena, Deepti Chatterjee, Kingshuk Khurana, Ananta |
author_sort | Sehgal, Virendra N |
collection | PubMed |
description | BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional supplements also play essential roles. Its diagnosis has been perpetuated by three or more major/minor criteria. OBJECTIVES: An endeavor to study its demographic and clinical pattern in contemporary prospective. MATERIALS AND METHODS: 100 fresh patients of atopic dermatitis, diagnosed on the basis of an established three or more major and minor criteria, salient presentations of which were recorded in a preset proforma, which also recorded age, duration, age of onset, and sex. Serum immunoglobulin E (IgE) levels were determined by conventional technique. The data thus obtained was analysed to study its clinical pattern and to correlate its severity to IgE levels. RESULTS: Its overall (new and old) prevalence was 0.98%, while that of new patients was 0.24%. 83 (83%) were in the age group of 2-12 years, of which 54 (83.1%) were males and 29 (82.9%) were female, of which 70 (70%) had urban, while 30 (30%) had rural background. Its duration varied from 8 to 192 weeks, with a mean of 76 weeks, and a standard deviation of 21.42 weeks [76 ± 21.42]. CONCLUSION: Atopic dermatitis is a discrete, overt, age and IgE-related entity frequently displaying varying demographic and clinical connotation. |
format | Online Article Text |
id | pubmed-4601437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46014372015-11-04 Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases Sehgal, Virendra N Srivastava, Govind Aggarwal, Ashok K Saxena, Deepti Chatterjee, Kingshuk Khurana, Ananta Indian J Dermatol E-IJD Original Article BACKGROUND: Atopic dermatitis is a distinct age-related clinical entity. Its etiopathogenesis is largely insubstantial. Nevertheless, it seems to be an outcome of interplay of maternal and inheritance, pregnancy/intrauterine and environmental factors. Besides, immune dysregulation, and nutritional supplements also play essential roles. Its diagnosis has been perpetuated by three or more major/minor criteria. OBJECTIVES: An endeavor to study its demographic and clinical pattern in contemporary prospective. MATERIALS AND METHODS: 100 fresh patients of atopic dermatitis, diagnosed on the basis of an established three or more major and minor criteria, salient presentations of which were recorded in a preset proforma, which also recorded age, duration, age of onset, and sex. Serum immunoglobulin E (IgE) levels were determined by conventional technique. The data thus obtained was analysed to study its clinical pattern and to correlate its severity to IgE levels. RESULTS: Its overall (new and old) prevalence was 0.98%, while that of new patients was 0.24%. 83 (83%) were in the age group of 2-12 years, of which 54 (83.1%) were males and 29 (82.9%) were female, of which 70 (70%) had urban, while 30 (30%) had rural background. Its duration varied from 8 to 192 weeks, with a mean of 76 weeks, and a standard deviation of 21.42 weeks [76 ± 21.42]. CONCLUSION: Atopic dermatitis is a discrete, overt, age and IgE-related entity frequently displaying varying demographic and clinical connotation. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4601437/ /pubmed/26538716 http://dx.doi.org/10.4103/0019-5154.164412 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | E-IJD Original Article Sehgal, Virendra N Srivastava, Govind Aggarwal, Ashok K Saxena, Deepti Chatterjee, Kingshuk Khurana, Ananta Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases |
title | Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases |
title_full | Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases |
title_fullStr | Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases |
title_full_unstemmed | Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases |
title_short | Atopic Dermatitis: A Cross-Sectional (Descriptive) Study of 100 Cases |
title_sort | atopic dermatitis: a cross-sectional (descriptive) study of 100 cases |
topic | E-IJD Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601437/ https://www.ncbi.nlm.nih.gov/pubmed/26538716 http://dx.doi.org/10.4103/0019-5154.164412 |
work_keys_str_mv | AT sehgalvirendran atopicdermatitisacrosssectionaldescriptivestudyof100cases AT srivastavagovind atopicdermatitisacrosssectionaldescriptivestudyof100cases AT aggarwalashokk atopicdermatitisacrosssectionaldescriptivestudyof100cases AT saxenadeepti atopicdermatitisacrosssectionaldescriptivestudyof100cases AT chatterjeekingshuk atopicdermatitisacrosssectionaldescriptivestudyof100cases AT khuranaananta atopicdermatitisacrosssectionaldescriptivestudyof100cases |