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Structural conservation of prion strain specificities in recombinant prion protein fibrils in real-time quaking-induced conversion

A major unsolved issue of prion biology is the existence of multiple strains with distinct phenotypes and this strain phenomenon is postulated to be associated with the conformational diversity of the abnormal prion protein (PrP(Sc)). Real-time quaking-induced conversion (RT-QUIC) assay that uses Es...

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Detalles Bibliográficos
Autores principales: Sano, Kazunori, Atarashi, Ryuichiro, Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601500/
https://www.ncbi.nlm.nih.gov/pubmed/26284507
http://dx.doi.org/10.1080/19336896.2015.1062201

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