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An active site–tail interaction in the structure of hexahistidine-tagged Thermoplasma acidophilum citrate synthase

Citrate synthase (CS) plays a central metabolic role in aerobes and many other organisms. The CS reaction comprises two half-reactions: a Claisen aldol condensation of acetyl-CoA (AcCoA) and oxaloacetate (OAA) that forms citryl-CoA (CitCoA), and CitCoA hydrolysis. Protein conformational changes that...

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Detalles Bibliográficos
Autores principales:	Murphy, Jesse R., Donini, Stefano, Kappock, T. Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2015
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601594/ https://www.ncbi.nlm.nih.gov/pubmed/26457521 http://dx.doi.org/10.1107/S2053230X15015939

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