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Subgroups of Paediatric Acute Lymphoblastic Leukaemia Might Differ Significantly in Genetic Predisposition to Asparaginase Hypersensitivity

L-asparaginase (ASP) is a key element in the treatment of paediatric acute lymphoblastic leukaemia (ALL). However, hypersensitivity reactions (HSRs) to ASP are major challenges in paediatric patients. Our aim was to investigate genetic variants that may influence the risk to Escherichia coli-derived...

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Detalles Bibliográficos
Autores principales:	Kutszegi, Nóra, Semsei, Ágnes F., Gézsi, András, Sági, Judit C., Nagy, Viktória, Csordás, Katalin, Jakab, Zsuzsanna, Lautner-Csorba, Orsolya, Gábor, Krisztina Míta, Kovács, Gábor T., Erdélyi, Dániel J., Szalai, Csaba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601692/ https://www.ncbi.nlm.nih.gov/pubmed/26457809 http://dx.doi.org/10.1371/journal.pone.0140136

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