Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model

Reactive cardiac fibrosis resulting from chronic pressure overload (PO) compromises ventricular function and contributes to congestive heart failure. We explored whether nonreceptor tyrosine kinases (NTKs) play a key role in fibrosis by activating cardiac fibroblasts (CFb), and could potentially ser...

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Detalles Bibliográficos
Autores principales: Balasubramanian, Sundaravadivel, Pleasant, Dorea L., Kasiganesan, Harinath, Quinones, Lakeya, Zhang, Yuhua, Sundararaj, Kamala P., Roche, Sandra, O’Connor, Robert, Bradshaw, Amy D., Kuppuswamy, Dhandapani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601773/
https://www.ncbi.nlm.nih.gov/pubmed/26458186
http://dx.doi.org/10.1371/journal.pone.0140273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601773/
https://www.ncbi.nlm.nih.gov/pubmed/26458186
http://dx.doi.org/10.1371/journal.pone.0140273

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