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High Affinity Binding of Indium and Ruthenium Ions by Gastrins
The peptide hormone gastrin binds two ferric ions with high affinity, and iron binding is essential for the biological activity of non-amidated forms of the hormone. Since gastrins act as growth factors in gastrointestinal cancers, and as peptides labelled with Ga and In isotopes are increasingly us...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601796/ https://www.ncbi.nlm.nih.gov/pubmed/26457677 http://dx.doi.org/10.1371/journal.pone.0140126 |