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6-Methoxy Podophyllotoxin Induces Apoptosis via Inhibition of TUBB3 and TOPIIA Gene Expressions in 5637 and K562 Cancer Cell Lines

OBJECTIVE: Podophyllotoxin (PTOX), a natural compound in numerous plants, contains remarkable biological properties that include anti-tumor, anti-viral such as anti-human im- munodeficiency virus (HIV) activities. In order to avoid its adverse effects, various com- pounds have been derived from PTOX...

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Detalles Bibliográficos
Autores principales: Sadeghi, Iman, Behmanesh, Mehrdad, Ahmadian Chashmi, Najmeh, Sharifi, Mohsen, Soltani, Bahram Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601871/
https://www.ncbi.nlm.nih.gov/pubmed/26464822