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Polarity establishment requires localized activation of Cdc42
Establishment of cell polarity in animal and fungal cells involves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region destined to become the “front” of the cell. The high local concentration of active Cdc42 promotes cytoskeletal polarization through vari...
Autores principales: | Woods, Benjamin, Kuo, Chun-Chen, Wu, Chi-Fang, Zyla, Trevin R., Lew, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602047/ https://www.ncbi.nlm.nih.gov/pubmed/26459595 http://dx.doi.org/10.1083/jcb.201506108 |
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