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The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources
The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building ba...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602064/ https://www.ncbi.nlm.nih.gov/pubmed/26373861 http://dx.doi.org/10.1007/s00335-015-9600-0 |
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author | Eppig, Janan T. Motenko, Howie Richardson, Joel E. Richards-Smith, Beverly Smith, Cynthia L. |
author_facet | Eppig, Janan T. Motenko, Howie Richardson, Joel E. Richards-Smith, Beverly Smith, Cynthia L. |
author_sort | Eppig, Janan T. |
collection | PubMed |
description | The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs. |
format | Online Article Text |
id | pubmed-4602064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-46020642015-10-16 The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources Eppig, Janan T. Motenko, Howie Richardson, Joel E. Richards-Smith, Beverly Smith, Cynthia L. Mamm Genome Article The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs. Springer US 2015-09-15 2015 /pmc/articles/PMC4602064/ /pubmed/26373861 http://dx.doi.org/10.1007/s00335-015-9600-0 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Article Eppig, Janan T. Motenko, Howie Richardson, Joel E. Richards-Smith, Beverly Smith, Cynthia L. The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
title | The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
title_full | The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
title_fullStr | The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
title_full_unstemmed | The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
title_short | The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
title_sort | international mouse strain resource (imsr): cataloging worldwide mouse and es cell line resources |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602064/ https://www.ncbi.nlm.nih.gov/pubmed/26373861 http://dx.doi.org/10.1007/s00335-015-9600-0 |
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