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Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism

Dopamine partial agonism and functional selectivity have been innovative strategies in the pharmacological treatment of schizophrenia and mood disorders and have shifted the concept of dopamine modulation beyond the established approach of dopamine D2 receptor (D2R) antagonism. Despite the fact that...

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Detalles Bibliográficos
Autores principales: de Bartolomeis, Andrea, Tomasetti, Carmine, Iasevoli, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602118/
https://www.ncbi.nlm.nih.gov/pubmed/26346901
http://dx.doi.org/10.1007/s40263-015-0278-3