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Lactate does not activate NF-κB in oxidative tumor cells

The lactate anion is currently emerging as an oncometabolite. Lactate, produced and exported by glycolytic and glutaminolytic cells in tumors, can be recycled as an oxidative fuel by oxidative tumors cells. Independently of hypoxia, it can also activate transcription factor hypoxia-inducible factor-...

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Detalles Bibliográficos
Autores principales:	Van Hée, Vincent F., Pérez-Escuredo, Jhudit, Cacace, Andrea, Copetti, Tamara, Sonveaux, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602127/ https://www.ncbi.nlm.nih.gov/pubmed/26528183 http://dx.doi.org/10.3389/fphar.2015.00228

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